The Application of Genetic Risk Scores in Age-Related Macular Degeneration: A Review.

نویسندگان

  • Jessica N Cooke Bailey
  • Joshua D Hoffman
  • Rebecca J Sardell
  • William K Scott
  • Margaret A Pericak-Vance
  • Jonathan L Haines
چکیده

Age-related macular degeneration (AMD), a highly prevalent and impactful disease of aging, is inarguably influenced by complex interactions between genetic and environmental factors. Various risk scores have been tested that assess measurable genetic and environmental contributions to disease. We herein summarize and review the ability and utility of these numerous models for prediction of AMD and suggest additional risk factors to be incorporated into clinically useful predictive models of AMD.

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عنوان ژورنال:
  • Journal of clinical medicine

دوره 5 3  شماره 

صفحات  -

تاریخ انتشار 2016